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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-367
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples and paired non-tumorous tissues; UM cell lines M17, M23, MUM-2B and C918; normal uveal melanocytes (um95)
Methods qRT-PCR, cell proliferation analysis, cell cycle assay, cell migration assay, luciferase reporter assay, Western blot
Expression pattern up-regulated
Functional description miR-367 was found to be upregulated in this malignancy, and may promote uveal melanoma cell proliferation and migration, at least in part by regulating PTEN.
PubMed ID 28829890
Year 2017
Title miR-367 promotes uveal melanoma cell proliferation and migration by regulating PTEN.
Drug-related ncRNA NO

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